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Clinicians should evaluate for contraindications specific to GLP-1 receptor agonists, including: Personal or family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 History of pancreatitis or gallbladder disease Severe gastroparesis or gastrointestinal disease History of suicidal ideation or behavior Pregnancy or planned pregnancy (pregnancy testing when appropriate) Diabetic retinopathy (requires monitoring in patients with diabetes) Baseline investigations should include TSH, free T4, complete metabolic panel, lipid profile, and hemoglobin A1c (if diabetic or prediabetic)

You may not eat enough B12-rich foods if you drink a lot

Others find that because theyre eating less foodone of the bodys natural sources of hydrationthey may unintentionally take in less water overall

However, lowering triglycerides in the MCS population has proven to be difficult with the currently available drugs utilized in lipid-lowering

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