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Importantly, tBHP-induced cell death and HMGB1 release were largely inhibited by classic ferroptosis inhibitors such as ferrostatin-1 (Fer-1) and deferoxamine (DFO), indicating the induction of ferroptosis (Fig

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Each experiment was conducted independently three times with duplicate measurements to ensure reproducibility and statistical robustness [1]

By around one month, patients see the biggest changes and are generally ready to show off their results in more body-conscious clothing