Furthermore, lipoic acid, an antioxidant with anti-inflammatory properties, attenuated oxidative stress and neurotoxicity in SOD1 G93A and SOD1 G85R Drosophila and cell culture models (Moura et al., 2015
Studies investigating muscle dysfunction in chronic fatigue syndrome have shown that patients exhibit an overreliance on this anaerobic metabolism even during low-level, everyday activities, leading to prolonged intramuscular acidosis and a slowed ability to clear protons from the tissue
Indeed, although IIEF-6 is a validated questionnaire distinguishing between presence or absence of ED by considering the whole spectrum of aspects related to penile erectile function, and also grading the severity of ED in clinical setting, it still remains a subjective tool, prone to the risk of recall bias, patients emotional drawbacks or patients conditioning due to uneasiness or misinterpretation of questions
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The one-sided Fishers exact test was applied
