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The frequency of administration of the full depot dose is usually between once per 4 weeks and once per week

Comparison of AAT and PR3 in individuals with or without AAV showed that in patients with PR3-AAV, but not those with MPO-AAV, elevated PR3 pools were quantitatively associated with ANCA titer, inflammatory response, and disease severity (161)

The existence and relative importance of vascular mimicry was initially debated and questioned in the field [64], but has since been supported by findings of several research groups [65]

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