Safety Considerations As with any compounded sterile injectable, prescribers should screen patients before administration: G6PD deficiency: Patients with known or suspected G6PD deficiency should be evaluated carefully, as IV glutathione and related sulfhydryl compounds have been associated with hemolysis in this population
Conversely, glutathione IV drips, while effective, require administration by a healthcare professional in a controlled environment
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We graded the overall certainty of the evidence using GRADE principlesconsidering risk of bias, inconsistency, indirectness, imprecision, and publication biasto help you and clinicians interpret how confident we are in the findings
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