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Hair takes a bit longer, but you may see changes around the 6-8 week mark with consistent daily use

Placing it in the refrigerator door where temperature fluctuates

However, vitamin B 12 deficiency does not generally develop until after at least two-to-three years of continuous therapy (137-139)

Effects of the MTHFR Mutation: Reduced Folate Metabolism: Folate (vitamin B9) is essential for many processes in the body, and MTHFR mutations can hinder the conversion of folate to its active form (5-MTHF)

If you get your hair removed often and notice that your skin is getting darker, this could be something to think about