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Supplementation of butyrate (all Sigma-Aldrich, Germany) was done in the drinking water at a final concentration of 150 mM and changed every 3 days and control mice received pH and sodium-matched water

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B12 deficiency can result from dietary factors such as a lack of animal products or from conditions affecting absorption like pernicious anaemia or gastrointestinal surgery

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10.1016/s1093-3263(00)00138-8 160 DunkerA