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As such, its important that weight-loss medication is used as part of a broader approach to healthy weight management, including access to appropriate nutrition, physical activity and behavioural support. Naveed Sattar, a professor of cardiometabolic medicine at the University of Glasgow, said: Expanding the range of effective treatments is important in helping people sustainably reduce caloric intakes within an increasingly obesogenic environment

Vitamin B12 deficiency is more commonly associated with long-term metformin use in type 2 diabetes patients and should be considered as an alternative explanation

International Journal of Obesity, 33 (4), 846856