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The formation of gamma-glutamylcysteine is the rate-limiting reaction in GSH synthesis and is feedback inhibited by GSH itself, a mechanism responsible for the regulation of cellular GSH concentration

It also improves memory and concentration

We therefore excluded the hypoxic cores and analysed the changes in ferroptosis-related proteins at day 100 (Fig

To this end, several ubiquitin ligases have been harnessed for targeted protein degradation (TPD), yet structural data on their ternary complexes remain scarce, limiting insight into the molecular basis of these interactions