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Insurance coverage will be a challenge if not expanded to include other conditions, one physician said, so FDA approval is paramount. This challenge echoes concerns of patients, who also list high costs as the primary obstacle to GLP-1RA treatment, according to The Cure GLP-1RA Report: Insights from Patients on GLP-1RA Medications and the Future of Obesity Treatment, which reports results of a survey of patients who had taken GLP-1RA medications

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Individual results vary based on adherence to lifestyle modifications and baseline metabolic health

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