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And for A1298C, the enzyme activity of heterozygous and homozygous mutant individuals are respectively 83 and 61% of the wild-type subjects 15 , as shown in Fig

The extrinsic apoptosis pathway is triggered by death receptor-death ligand interactions, including FasL/FasR, TRAIL/TRAIL-R1 or TRAIL-R2, and TNF/TNF-R1 [77,78,79]

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