Moreover, we observed that GCGR mAb increased beta cell mass and proliferation (a main source of regenerated beta cells in adult rodents [30]) in WT and Flox diabetic mice, while these effects were attenuated in Fgf21 / and Fgf21 Hep/ diabetic mice, suggesting that FGF21 contributed to the promoting effect of GCGR mAb on beta cell regeneration
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(2) Ernest Adeghate and Abdul Samad Ponery (2004) Mechanism of ipamorelin-evoked insulin release from the pancreas of normal and diabetic rats Neuro Endocrinology Letters, 2004 Dec, Volume 25 (Issue 6), Pages 403-6