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Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015

Behind Novo and Lilly: The Emerging GLP1 Challengers While Novo and Lilly lead the global GLP1 race, new challengers across the U.S., India, and China are rapidly gaining ground

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OHara AM, Shanahan F

While the top of TM6 and ECL3 could not be confidently modelled for the exendin-4 complex, the portion of TM6 and TM7 that were modelled, along with the weak density corresponding to ECL3 supports a backbone conformation more similar to GLP-1 and oxyntomodulin bound receptors, rather than exendin-P5, albeit it is likely that this region is more conformationally dynamic