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Additionally, GLP-1RAs were recognised for their remarkably significant impact on weight reduction in both diabetic and non-diabetic overweight and obese patients (30)

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however, GLP-1 receptor agonists (GLP-1RAs) have been developed to prolong its activity and maximize its metabolic benefits

GLP-1R distribution in the cardiovascular system GLP-1R is a member of the class B1 family of G protein-coupled receptor for which there are only predicted structures [30]