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According to the authors, these findings add to growing scientific evidence exploring the potential role of GLP-1 receptor agonists in alcohol use disorder

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The gastrointestinal tract and brain maintain a crosstalk connection in which gut microbiota and inflammatory response are crucial, and this immune disruption is inextricably related to a neuroinflammatory response mediated by abnormalities in microglia and mitochondrial functions, as well as an increase in oxidative damage