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Several participants reflected on improvements in a range of physical health issues including breathlessness, back pain, frequent urination and urine infections, sleep, and skin problems

Notably, we observed a 2- to 3-fold increase in melanocortin-4 receptor ( Mc4r ) and neuropeptide Y2 receptor ( Npy2r ) expression in Bbs5 / mice

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These iron-containing proteins participate in numerous biological processes, including metabolism, biocatalysis, electron transport within the respiratory chain, oxygen transport, energy maintenance, and immune regulation [4,5,6,7]