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The clinical connection to muscle loss is direct when lean tissue decreases rapidly, facial changes are amplified

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Studies have shown that impaired levels of insulin and an increase in insulin resistance lead to increased adipose lipolysis and FFA release into the circulation and their enhanced hepatic uptake, subsequently causing fat accumulation in the liver (Zhong et al., 2012

In addition to these serious side effects, Contrave may also cause seizures, liver problems, and visual problems