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Common adverse effects associated with probiotic use are typically mild and gastrointestinal in nature: Bloating and gas, especially during the first few days of use Abdominal discomfort or cramping Changes in bowel habits (diarrhea or constipation) Nausea (less common) These symptoms usually resolve within one to two weeks as the gut microbiome adjusts

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The proposed mechanism centers on the gut microbiome's role in metabolic regulation

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One study found that four percent of Americans are taking GLP-1s, which reflects a 600 percent increase in the last five years