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a recent safety analysis found no anaphylaxis in hundreds of patients receiving high-dose IV thiamine, suggesting the risk is very low in practice

While this idea is somewhat simplified, its intriguing His hypothesis suggests that the sudden influx of B12 can kickstart repair processes, and if there has been long-standing damage, the rapid onset of these processes might overwhelm the system, causing a temporary worsening of symptoms

These symptoms often build up slowly, making them easy to overlook

While medication one day past the BUD may still be effective, you have no way to verify this without laboratory testing

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