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The Numbers Dont Lie A 2025 systematic review published in HSS Journal did what science is supposed to do: they screened the entire published literature on BPC-157 from an orthopaedic sports medicine perspective

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While preclinical studies suggest neuroprotective benefits, long-term clinical data in humans are limited, and further research is needed to determine whether these effects occur via the gut-brain axis or direct antioxidant activity

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In the presence of high concentrations of polyamines the ribosome frameshifting occurs resulting in the synthesis of functional antizyme 1 which comprises amino acids from both ORF1 and ORF2