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These minor reactions are typical, but its important to recognize when something more serious might be happening

DPP-IV cleaves the Ala2-Asp3 bond in vivo, limiting plasma half-life to approximately 10-20 minutes [3][5]

Antidepressants and gut microbiota Nowadays, neither monotherapy nor the use of antidepressants in rapid cycling BD is recommended, but antidepressants can be used as adjunctive treatment in BD as a second-line treatment

These symptoms generally emerge around four weeks after starting treatment

Presently, there is no definitive clinical data for reactive metabolite-forming antidepressants that can pinpoint the exact cause of hepatotoxicity