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Genetic polymorphisms affecting GPx and other antioxidant enzymes, such as superoxide dismutase, have been implicated in susceptibility to conditions including coeliac disease

N Engl J Med 349:16051613 Upchurch GR Jr, Welch GN, Fabian AJ, Freedman JE, Johnson JL, Keaney JF Jr, Loscalzo J (1997) Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase

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