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Polymorphisms in various genes involved in vitamin B 12 metabolism, including the genes encoding the intrinsic factor-cobalamin receptor (60) and the holo-transcobalamin receptor (61), have been associated with increased NTD risk in some studies

After repeated IM administration of BPC157 at 100 g/kg for seven consecutive days, the plasma concentration versus time curve (Figure 1C) and pharmacokinetic parameters (Table 3) were similar to those observed after a single IM injection at a dose of 100 g/kg, except for a slight increase in C max and AUC 0t

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