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Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelial-to-mesenchymal transition

Pribyl AL, Hugenholtz P, Cooper MA (2025) A decade of advances in human gut microbiome-derived biotherapeutics

Two trials in acutely hospitalized patients have shown that short-term (around 7 days) vitamin C supplementation increased concentrations of ascorbic acid in plasma and leukocytes and led to 34-35% improvements in mood state, as measured by POMS (142, 143)

Lowering the buildup of toxins can translate to less cellular damage, which in turn can support a healthier biological age

A pronounced decline was observed in the wall area, the wall thickness of the bronchioles, the wall area/total bronchiole area (MA%) and the wall thickness/bronchiole diameter (MT%) in lung tissues of COPD rats treated with NAC + oe-VWF compared with those treated with individual oe-VWF (Fig