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Images were obtained on a Zeiss AxioImager Z1 epifluorescence microscope with 20 or 63 oil immersion objective and analyzed using Zeiss ZEN Blue microscopy software

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A Phase 3b, Randomized, Multicenter, Controlled Study of Mirikizumab and Placebo or Mirikizumab Concomitantly Administered With Tirzepatide in Adult Participants With Moderately to Severely Active Crohns Disease and Obesity or Overweight [Internet]

But the direction of travel is reassuring, not alarming

Studies show that a high concentration of free radicals, including NO, exists within the inflammatory demyelination lesions of MS (26)