The method of embodiment 81, wherein the external beam radiation therapy is three-dimensional conformal radiation therapy (3D-CRT), image guided radiation therapy (IGRT), intensity modulated radiation therapy (IMRT), helical-tomotherapy, photon beam radiation therapy, proton beam radiation therapy, stereotactic radiosurgery, stereotactic body radiation therapy (SBRT), or intraoperative radiation therapy (IORT)
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It was also demonstrated that lipid metabolism promoted ferroptosis in the HTGP process by regulating ACSL4/LPCAT3 levels, and that ER stress may be involved in ferroptosis through the BIP/p-EIF2/CHOP pathway
