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Recently, the Philippine Dermatological Society issued a disclaimer warning against the unprofessional use of the substance as a skin whitener

These effects are generally mild to moderate in severity, but they can lead to treatment discontinuation in approximately 4-7% of patients

PMID 12663437

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Although both dysregulated hepatic glutathione homeostasis and TNF overproduction are critically involved in the development of NAFLD, whether they can be synergistically implicated in hepatocyte death remains to be clearly defined