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The trial targeted people who are overweight or obese who have high cardiovascular risk but not diabetes

It also outlines clinical monitoring based on symptom timing and severity

According to the MHRA-approved SmPC, the most frequently reported side effects are gastrointestinal in nature and include: Nausea (very common, affecting more than 1 in 10 people) Diarrhoea (very common) Constipation (very common) Vomiting (very common) Abdominal pain (very common) Headache (very common) Fatigue (common, affecting up to 1 in 10 people) Dyspepsia (indigestion, common) These gastrointestinal effects typically occur during dose escalation and often improve as the body adjusts to the medication

Low blood sugar Going to bed hungry or experiencing overnight blood sugar dips can make it harder to sleep

This method provides healthcare providers with valuable insights into how each individual responds to the medication, enabling them to tailor the approach further based on specific reactions and needs