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Glutathione also plays a role in melanin regulation

The WGCNA approach, applied to this set of microarray data, clusters co-regulated genes based on their co-expression pattern and organizes them into modules. An eigengene score is thereafter applied to each module derived from the z-scored log 2-fold change values of the genes consisting the module (module membership)

Copper ions serve as cofactors for various enzymes and are involved in the regulation of immune cell activity and oxidative stress responses, thereby potentially affecting the functions of critical immune cells, such as dendritic cells (DCs)

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