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Table 1 below depicts some of the more prolific GLP-1 drugs approved by the FDA

In humans, immunohistochemistry using a monoclonal antibody showed that the GLP-1 receptor protein is expressed in the pancreas, in smooth muscle cells of the kidney, lung, and gastrointestinal (GI) tract, and in myocytes of the heart [16]

Heartburn and reflux: Food and stomach acid remaining in the stomach longer can worsen acid reflux symptoms

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Although there are data in animal models supporting that this is true, particularly in diet-induced obese mice, in which brown adipose tissue activity is regulated [8], there is no convincing evidence that this occurs in humans [6]