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More systemic side effects, such as weight gain and high blood pressure, may develop over days or weeks of continued use

Strategies to Prevent Rapid Weight Regain After Stopping GLP-1 The most evidence-supported approach is gradual dose reduction rather than abrupt cessation

Published 2021 Mar 25 Ramos Gonzalez M, Axler MR, Kaseman KE et al (2023) Melatonin supplementation does not alter vascular function or oxidative stress in healthy normotensive adults on a high sodium diet

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