Search terms included combinations of GLP-1 receptor agonist, semaglutide, liraglutide, tirzepatide, cutaneous side effects, dermatology, hidradenitis, psoriasis, bullous pemphigoid, facial aging, and plastic surgery. Of 260 articles initially identified, 155 were included on the basis of predefined eligibility criteria prioritizing randomized controlled trials, observational studies, systematic reviews, regulatory reports, and clinically relevant case series in adult populations
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Dose Escalation GLP-1 medications are typically introduced at a low dose and increased gradually
The practical alternative is strict adherence to storage guidelines combined with vigilant visual inspection
Dont take without supervision, particularly if pregnant, as evidence is lacking