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Thus, in the well-fed state, insulin enhances the carbon flux through the pentose phosphate pathway, increasing NADPH production Note: insulin also promotes fatty acid synthesis, which depends on a continuous supply of NADPH

Specifically, miR-26a was demonstrated to modulate CRC glucose metabolism by targeting PDHX, inhibiting the conversion of pyruvate to acetyl coA in the TCA cycle (108)

focused on bioactive lipid families in an in vitro model of OA, demonstrating the involvement of specific lipids in the inflammatory response [151]

Confocal microscopy A Zeiss LSM980 confocal microscope operated using the ZEN3.6 blue edition software (Carl Zeiss AG, Oberkochen, Germany) was used for plant cell imaging