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It has also been suggested that part of the anorectic effects of GLP-1 could result from its side effects such as nausea and inhibition of gastric emptying [85-87]

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The clinical relevance of Wegovy reflects the convergence of three highburden conditionsobesity, cardiovascular disease, and metabolic liver diseasewhere weight reduction and metabolic improvement can modify longterm outcomes but where durable, nonsurgical options have historically been limited

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