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Another study published in Behavioural Brain Research reported that Dihexa administration reversed memory loss in a mouse model of Alzheimers disease, suggesting its potential in neurodegenerative disease conditions
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The authors suggest an implication of the phosphorylated CREB, mediated by PI-3K and MAPK signaling pathways, that is known to decrease neurotoxicity and oxidative stress-induced neuronal death (Du and Montminy, 1998
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