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Besides being the bodys primary water-soluble antioxidant and a major detoxification agent, glutathione is absolutely essential for the functioning of the immune system

Lesional KP is also differentiated from non-lesional KP in biopsies taken from lesional KP sites where it's been observed that sebaceous glands are in the process of atrophy or are already completely disintegrated

The content of Fe 2+ is strictly regulated, and when its level is out of balance, excess ferrous will provide electron-promoting lipid peroxidation via Fenton reaction, resulting in an increased production of ROS and inducing ferroptosis (Kajarabille and Latunde-Dada 2019