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These iron ions can exacerbate oxidative stress by catalyzing Fenton and Haber-Weiss reactions, leading to the production of ROS and reactive nitrogen species, which subsequently cause damage to brain cells (Fila et al., 2024)

In light of these considerations, future investigations should prioritize the following directions

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For example, it has been shown to: Decrease levels of DNA damage when administered to senescence-accelerated mice [15]

The short version: KPV has a mechanistically interesting anti-inflammatory profile through melanocortin receptor agonism and direct NF-B suppression