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Because while ingredients like niacinamide have worked well for me before, Ive experienced some unpleasant stinging from vitamin C in the past meaning Ive always been on the fence when it comes to brightening products

Case reports describe serious systemic toxicity and rhabdomyolysis at mega-doses (around 6 mg) [4]

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Notably: 2 cases of rash occurred in the transdermal group