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Cardiovascular benefits: Clinical trials have demonstrated that tirzepatide can reduce the risk of major adverse cardiovascular events, such as heart attacks and strokes, in people with type 2 diabetes who have established cardiovascular disease

Key takeaways: Carnitine transports fat into mitochondria but is not usually the limiting factor Supplementing carnitine alone shows little benefit in most people Choline helps increase and retain carnitine in muscle tissue Combining choline and carnitine improves fat mobilization Adding caffeine further enhances energy expenditure and fat oxidation If a supplement claims to burn fat with carnitine alone, its likely missing the bigger picture

J Neurosci 30: 45524561

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