My advice to clinicians is to proactively discuss contraception when initiating GLP-1 therapies in women of child-bearing age, document pregnancy intentions, and give pre-conception wash-out advice as per FSRH guidelines, said Dr Cheung
Those with pancreatic disorders, inflammatory bowel disease, or known allergies to pork or beef products should consult their healthcare provider before using enzyme supplements
Small changes that are repeated daily change what the colon sees, shift microbial fermentation patterns, and over weeks to months can raise SCFA production and contribute to more consistent GLP-1 signaling
Selpercatinib and pralsetinib have shown remarkable efficacy, including a few complete responses and favorable safety in phase 1/2 trials
High-quality longitudinal micronutrient outcome studies in GLP-1 populations remain limited