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The fat is leaving

Receptor-interacting protein kinase1 (RIPK1) is a central regulator of cell death pathways, including apoptosis, necroptosis, and inflammation (Ofengeim et al., 2017)

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Taken together, the current evidence suggests that the therapeutic value of tirzepatide lies not only in achieving substantial weight loss, but also in preferentially reducing metabolically deleterious fat depots while relatively preserving lean tissue, with the potential for additional cardiometabolic and renal benefits