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Abstract Dipeptidyl peptidase-4 (DPP-4) is an important protease that is widely expressed on the surface of human cells and plays a key role in immune-regulation, inflammation, oxidative stress, cell adhesion, and apoptosis by targeting different substrates

Semaglutide is a highly effective medication for managing type 2 diabetes and aiding in weight loss

New decision-making processes for the pricing of health technologies in Japan: the FY 2016/2017 pilot phase for the introduction of economic evaluations

While licensed by the MHRA, NICE recommends semaglutide for weight management only within specialist weight management services and under more restricted BMI criteria than the licence

Early research suggests it may lead to more significant weight loss than semaglutide