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[21] [22] Bariatric surgery represents the most effective long-term intervention for severe obesity

doi: 10.1177/1060028020935105 127 LinSDengYHuangJLiMSoorannaSRQinMet al

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While JAK inhibitors are effective in treating patients with IBD, psoriasis, and psoriatic arthritis [41, 42], this drug class is generally associated with an increased risk of mortality, serious infections, malignancy, and major adverse cardiovascular events, which limit their use in certain populations [2224, 4244]