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Always use a new needle for each injection, never share pens between patients, and follow proper sharps disposal guidelines

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At week 4, an 83% (11.1 U/day) reduction in TDD was due to a direct drug effect, and 17% (2.3 U/day) was attributed to weight loss, whereas at week 26, the difference was split evenly between direct effect (11.4 U/day

Cardiometabolic Safety: Assessing cardiovascular and renal outcomes in animal models to inform human safety profiles