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Complementary human atlas data integrating snRNA-seq and single-cell assay for transposase-accessible chromatin using sequencing (scATAC-seq) further resolved quiescent, early primed, late primed, and differentiating MuSC states, showing that aging skews the balance toward prematurely primed ( FOS + , JUN + ) MuSCs and providing evidence for progressive exhaustion of the stem cell pool

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