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This approach helps identify any sensitivity while still providing therapeutic levels

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267,268 p53 inhibits the differentiation of WAT in several in vitro models and protects against diet-induced obesity in vivo

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Since T315I-Bcr-Abl-transformed 32D cells took longer time to develop leukemia phenotype than WT Bcr-Abl cells, we transplanted 2-fold more cells into C3H/HeNCrNarl mice