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This article explores the scientific evidence, clarifies when B12 supplementation might be associated with anxiety-like symptoms, and provides guidance on safe management aligned with UK clinical practice and NICE recommendations

Last reviewed: June 15, 2026 Last updated: June 15, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Cell images were captured at 0, 8, 18, and 30 h by fluorescence microscope

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