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The mechanism is primarily neurological and metabolic: semaglutide reduces appetite, improves satiety after smaller meals, and reduces the reward-driven food cravings that make sustained caloric restriction difficult for most people

What Stays the Same in 2026 Weight loss exclusion continues on commercial and Medicare plans (unless BALANCE changes this) OSA coverage continues for Medicare members (AHI 15, BMI 27, no diabetes) Diagnosis code edits remain active claims still auto-reject for obesity codes For the latest Medicare policy details, see our Medicare coverage guide

A recent trial showed that even moderate protein insufficiency during GLP-1 use correlated with sarcopenia markers

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The actual injection only takes a few seconds