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In a rodent model for obesity, tirzepatide administration induced a loss of body weight, by mechanisms of reducing food intake and by increasing energy expenditure (57)

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Without medical monitoring, the person may not recognize the symptoms until they are in crisis

Tirzepatide has demonstrated cardiovascular safety with potential benefits including modest blood pressure reductions (3-7 mmHg), improved lipid parameters, and a small increase in resting heart rate (2-4 bpm)

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