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Wnt/-catenin pathway in lung-associated non-cancer diseases Normal lung development and differentiation are inseparable from the regulation of the Wnt/-catenin signalling pathway, but the imbalance of this pathway often promotes the occurrence of some lung diseases, including tumour and non-tumour diseases

Gicquel, T., Aubert, J., Lepage, S., Fromenty, B

Observations in murine models of GHRH gene ablation point to possible normalization of growth indicators, including body weight, bone length, and lean mass, with concurrent increases in pituitary RNA and GH mRNA levels

Key points Human IGF-1 and LR3 IGF-1 are produced in the P